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Dickey’s lab commenced studying mucin secretion two decades back and Earlier recognized The crucial element genes and proteins involved, displaying how synaptotagmin as well as a SNARE advanced, similar to that found in neurons, contribute to The real key strategy of Ca2+-induced membrane fusion.
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De novo variants in SP9 lead to a novel type of interneuronopathy characterised by intellectual disability, autism spectrum dysfunction, and epilepsy with variable expressivity.
Usually, mucins are step by step introduced in to the airways, wherever they absorb water and type a thin layer of protecting mucus that traps pathogens and is easily cleared by cilia.
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